The cytoplasm is protoplasm that surrounds the nucleus. All the organic substances of the cell are referred to as the protoplasm. The cytoplasm and the nucleus make up the protoplasm.
No, they are not interchangeable because p<span>rotoplasm is the living content of a cell that is surrounded by a plasma membrane (cell membrane). Protoplasm is composed of a mixture of small molecules such as ions, amino acids, monosaccharides and water, and macro-molecules such as nucleic acids, proteins, lipids and polysaccharides. In eukaryotes the protoplasm surrounding the cell nucleus is known as the cytoplasm and that inside the nucleus as the nucleoplasm. </span>
