A genetic test to detect predisposition to cancer would likely examine the APC gene for involvement in colorectal cancer.
Adenomatous polyposis coli is known as APC. An individual has a higher lifetime chance of developing many colorectal polyps (from ten to hundreds) as well as colorectal cancer if they have a genetic mutation that interferes with the operation of the APC gene. Colon cancer can strike anyone at any age, but it often strikes older persons. Small, benign (noncancerous) cell clusters called polyps commonly grow on the interior of the colon as the first signs of the condition. Some of these polyps may eventually develop into colon cancer.
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