The generation of the action potential requires the change in the membrane potential of the cell. This membrane potential is maintained due to the unequal distribution of the ions.
The cell potential of the cell is -70mV and maintained due to the presence of potassium ions. The depolarization occurs due to the influx of the sodium ions and results in the change in the membrane potential upto +30mV. The neurotoxin that interferes with depolarization process might affect the sodium ions uptake.
The answer is the food web would be affected and many populations of species would start to die off. Food web affects the aquatic plants that feed more the species of fish and every aquatic life. The population would decrease.