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Answer:
The individual calcium atom has a positive, not negative, 2 charge.
Explanation:
The error in her study is in the second line of her note which suggests that the individual calcium atoms becomes ions with a negative 2 charge.
- When atom loses electrons, it has a net positive charge on it.
- Not a negative charge.
- This is because the number of protons is now more than electrons.
- Therefore, a net charge on the calcium atom will be a positive one.
- This is her mistake.
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Answer:
Taxol alters cytosolic calcium signaling by opening mitochondrial pores
Explanation:
Taxol is an antimitotic (i.e., cytotoxic) agent used in chemotherapy to kill cancer cells. Taxol is an antimitotic drug that has been successfully used in different types of cancer including ovarian cancer, breast cancer, pancreatic cancer, sarcoma, etc. Recently, it has been shown that Taxol may induce rapid cytosolic calcium (Ca2+) response by producing a decrease in mitochondrial membrane potential associated with the loss of mitochondrial Ca(2+). In consequence, it has been proposed that the side effects of chemotherapy might be associated with the action of cytotoxic agents such as Taxol which alters mitochondrial function and Ca(2+) signaling cascade.