Question

Note the coding effect of the mutation found in kindred group 2082. This results from a single base-pair substitution. Choose the normal double-stranded sequence for this codon (with the and ends labeled) and the sequence after the mutation that resulted from an uncorrected mismatch event during DNA replication.
5 ′ -CAG(A)- 3 ′ coding 3 ′ -GTC(T)- 5 ′ template changed into 5 ′ -TGA- 3 ′ coding 3 ′ -ACT- 5 ′ template 5 ′ -TAC(T)- 3 ′ coding 3 ′ -ATG(A)- 5 ′ template changed into 5 ′ -TAG(A)- 3 ′ coding 3 ′ -ATC(T)- 5 ′ template 5 ′ -TGG- 3 ′ coding 3 ′ -ACC- 5 ′ template changed into 5 ′ -TGA- 3 ′ coding 3 ′ -ACT- 5 ′ template 5 ′ -CAG(A)- 3 ′ coding 3 ′ -GTC(T)- 5 ′ template changed into 5 ′ -TAG(A)- 3 ′ coding 3 ′ -ATC(T)- 5 ′ template

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