Answer:
The answer is reciprocal chromosomal translocation
Explanation:
The Philadelphia chromosome (Ph) is the truncated chromosome 22 generated by the reciprocal translocation t(9;22)(q34;q11) and was first identified in 1960 in a patient with CML [3]. Translocation of the proto-oncogene tyrosine-protein kinase (ABL1) gene located on chromosome 9 to the breakpoint cluster region (BCR) gene located on chromosome 22 results in a BCR-ABL1 fusion gene on the Ph [4, 5]. Three BCR-ABL1 fusion gene hybrids encode BCR-ABL1 protein isoforms p210, p190, and p230, which have persistently enhanced tyrosine kinase (TK) activity. These aberrantly activated kinases disturb downstream signaling pathways, causing enhanced proliferation, differentiation arrest, and resistance to cell death [6, 7]. Tyrosine kinase inhibitors (TKIs) targeting the BCR-ABL1 protein are the most successful targeted therapy for Ph-positive leukemia.
Answer:
1. traditional health records
2. health information management
3. health informatics
4. information technology
Explanation:
just did it
Nervous tissue is found in the brain, spinal cord, and nerves. It is responsible for coordinating and controlling many body activities. It stimulates muscle contraction, creates an awareness of the environment, and plays a major role in emotions, memory, and reasoning.
Explanation:
1)
building blocks of Carbohydrates are monosaccharides that are simple sugars
2)amino acids are the building units of proteins there are 20 amino acids found in human body that are building blocks of proteins
3)Nucleotides are the building blocks (monomers) of nucleic acids, DNA and RNA.
<span>Great minds combined with technological advancements have a lead to creations and achievements that would have been impossible. Whatever great scientist of the past has achieved have already been surpassed or improved through modern and innovative ideas and processes. An excellent example of which is the direct manipulation of an organism’s DNA, also known as genetic engineering or genetic modification (GM). Coming from the terms genes and modify, the entire process is something out of a science fiction movie. Well, it used to be that way until the practice was perfected and used in actual applications. Genetic engineering made it possible to add new DNA or alter bad ones.</span>
