Answer:
Answer explained
Explanation:
a. Overexpression of Axl receptor tyroxine kinase correlates with the decresed patient's overall survival and hence it's inhibition is under process.
AXL TKI BMS777607 treatment increased AXL protein levels after 24 h as observed by Western blot and flow cytometry analysis. Mechanistically, this inhibition-induced AXL cell surface accumulation was neither associated with epigenetic modifications, nor altered transcriptional and translational regulation. Hence this later increased the glycosylated protien abundance in kinase dead mutant. The kinase function blockaging resulted in impaired internalisation which finally incresed the level of proliferation.
An alternative technique may exist in linkage of Axl Tkl to a degradation machinery recruitment unit .
b. Mendelian disorders like cystic fibrosis results from error in the given DNA sequence which can be autosomal dominant and recessive both and also X or Y linked. Mutated gene results in the Mendelian disorders. Whereas in cancer there can be mutation or proliferation of the given cells in a specific area. In cancer cells there is 2.5 times more the mRNA present while 6.2times the DNA and hence the detection and diagnosis automatically becomes difficult as in Mendelian disorders only single sequence needs to be studied at a time .
I would say A just because if your dad has a genetic disease and you mom does not have it you have about a 50 50 chance of having that disease in a perfect control that's assuming that its recessive and that your moms side does not present this disease
that's how its always been taught to me
Answer:
A. We can deduce that microorganisms such as Citrobacter have a classification from which it is possible to establish the most favorable environment for it, since being gram-negative, lactose positive, optional anaerobic, not endospore, it will prefer the environment as humid sites and that contain wastewater and soil as well as the intestine, it can therefore remain in some contaminated food and be transmitted with consumption
B. Given the aforementioned characteristics of Citrobacter, it does not infect all people and prefers those who have deficits in its defense mechanisms, thus it becomes a favorable site for colonization of newborns, who do not have adequate immunity, according to the case. Clinically, the neonate was able to acquire the infection in various ways, although the medical personnel who have manipulated it do not have positive tests, the microorganism can adhere to contaminated surfaces and it will be necessary to take samples of the mother's and neonate's feces, as well as the soil. and the water where the infected was, to subsequently carry out disinfection processes in the areas and avoid new infections.
Answer: It happened from Apr 20, 2010 – Sep 19, 2010
Explanation:
Answer:
Humans have some stem cells, but those cells are not easily available to help with healing. Most other mammals are the same, so they aren't good at regeneration either. Amphibians and some fish have stem cells that are more easily available, and are usually pretty good at regeneration.