Look out for angioedema (like hives but a deeper swelling due to an allergic reacrion), bleeding (such as intracranial, gastrointestinal and genitourinal hemorrhaging) and adverse reactions to drugs. Nausea, blood pressure spikes, severe headaches, acute hypertsnsion, etc are other signs of negative reacrions to iv t-pa as well.
Answer:
(1) Bromination, (2) E2 elimination and (3) epoxidation
Explanation:
- In the first step, -OH group in cyclopentanol is replaced by more facile leaving group Br by treating cyclopentanol with

- In the second step, E2 elimination in presence of strong base e.g. NaOEt/EtOH produce cyclopentene
- In the third step, treatment of cyclopentene with mCPBA produces 1,2-epoxycyclopentane
- Full reaction scheme has been shown below
Well, the sun is in space, right? It has to be able to transfer heat through space, or how would it get to us? Radiation helps transfer heat.