<span>By combining it with its wild respective realtive to avoid acquiring diseases. or It can save a crop plant by altering its structure, so it can repel diseases</span>
Answer:
Gene knockout is a technique used to determine the function of a gene that has already been sequenced, which is achieved by analyzing the phenotype of the individual carrying the knockout mutation(s). Moreover, gene sequencing is a technique used to determine the sequence of a given gene, which allows to determine how gene variants (polymorphisms) may be associated with the phenotypes of the target trait.
Explanation:
In genetics, gene knockout is a technique used to trigger mutations in a (already) sequenced gene in order to inactive its function and observe the resulting phenotype for a particular trait. This approach that starts with the inactivation of a given gene and ends with the phenotype is known as reverse-genetics. On the other hand, gene sequencing can be defined as the methodologies/techniques/tools used to determine the nucleotide base pair sequence of a particular gene. The gene knockout technique involves knowing a priori the gene sequence in order to obtain a gene knockout (gene KO). The combination of the information obtained from these techniques can be used to determine how variation (genetic variation) affects the expression of a phenotypic trait.
Answer:
mutation rates can be used to design molecular clocks in order to estimate divergence times among species
Explanation:
In evolutionary biology, the substitution rates (also known as mutation rates) are used for the development of 'molecular clocks' which allow estimating the divergence times among species or among taxonomic groups. Molecular clocks can be designed by estimating the divergence rate of nucleotide sequences (either DNA or RNA) and amino acid (protein) sequences. These substitution rates can also be used to track how quickly viruses evolve (for example, in a pandemic situation).