Answer:
The effect of amanitin on the maximum elongation rate for the wild-type and modified RNA polymerases is that it binds to the RNA polymerases, and reduces the process of translocation which is essential for RNA synthesis that is required for RNA polymerases elongation.
Explanation:
Amanitin is a peptide that is cyclic in nature. It is repelled by water thereby making it an hydrophobic peptide.
Amanitin is a toxic peptide that is found in Amanita ( a type of mushroom).
Alpha Amanitin in particular is the one that affects the elongation rate of RNA Polymerases in the body.
When Alpha Amanitin gets into the body system, it travels straight to the liver and due to its very strong affinity for RNA polymerases, it immediately attaches itself to them.
After the attachment, Alpha Amanitin, is disturbs the bridge helix found in RNA polymerase, preventing the hindering and slowing down the proces of translocation from happening.
Once translocation is hindered, RNA is no longer synthesized. Hence, the elongation of RNA polymerases is hindered and this results in severe illness in the body such as liver failure, cytolysis of the liver
Plasmodesmata can change in number, and when dilated can provide a passageway macromolecules
Plasmodesmata are essential for the intercellular transfer of both big informational macromolecules like proteins and smaller signaling chemicals in plant cells.
- Plasmodesmata are membrane-lined structures that offer a high-conductance, aqueous channel for the transportation of information in the form of chemicals and macromolecules, such as transcription factors, from cell to cell.
- The intimate interaction of the plasma membrane with the endoplasmic reticulum results in the formation of plasmodesmata.
- The degree to which a particular cell acts as an individual or as a component of the entire organism is determined by the distribution and unitary conductance of plasmodesmata as well as other positional variables that affect development.
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Definition cell, nucleus, chromosome, DNA, nucleotide