Answer: Clathrin cages assemble, vesicles form but cannot be pinched of but no disassembly occurs so the vesicles remain coated in clathrin.
Explanation:
Endocytosis is a cellular mechanism that allows the introduction of extracellular material into the cell. Clathrin-coated vesicles act to incorporate different molecules that are recognized by specific proteins located in the clathrin-coated pits. Upon invagination of a portion of the plasma membrane, the material is transported to its final intracellular destination.
<u>Clathrin is a protein that forms the lining of cell membrane microcavities where various receptors are located. Once a particle is recognized by the receptors, invagination of the plasma membrane occurs, which then fuses to form an endocellular vesicle.</u> When vesicle budding occurs, the vesicle is detached from its attachment to the membrane with the help of a GTPase protein called dynamin. Then, the vesicle is freed from clathrin by the action of a type of ATP-ase called Hsp70-ATP and docks to late endosomes that are immediate precursors of lysosomes, fusing the membranes of both. The fission of the clathrin-coated vesicle is controlled by the GTPase dynamin and it has been proposed that dynamin acts by generating the necessary force to strangle the "neck" and cleave the vesicles from the membrane. So they are mainly involved in the cleavage of newly formed vesicles from the membrane of one cell compartment, their orientation, and their fusion with another compartment. Also, without the dynamin, vesicles are not freed from clathrin.
<u>In the absence of dynamin, vesicles are formed but the membrane fusion or pinching off will not occur. Then, invaginated coated pits will be found.</u>
Answer:
Explanation:
chaperonins
Members of the Hsp60 family (also called chaperonins) facilitate the folding of proteins into their native conformations. Each chaperonin consists of 14 subunits of approximately 60 kilodaltons (kd) each, arranged in two stacked rings to form a “double doughnut” structure
Answer:
The wechsler intelligence scale for children (WISC) is a good indicator of innate "genetic" ability for children of six to sixteen years old.
Explanation:
Wechsler Intelligence Scale for Children (WISC) is basically a system of testing IQ of children from six to sixteen years old. This testing was created by David Wechsler, who stated that intelligence is a global quality and it should be reflected in children's verbal as well as non-verbal abilities.
This testing system is used by schools for several purposes:
• To evaluate the performance of kids during placement process.
• It is also used to evaluate abilities of dis-abled children or deferentially able children.
• IQ scores from WISC can be used to diagnose the problems of the children such as mental re-tardation or some specific learning dis-ability. It can also be used to determine the problems of the children who face hyperactivity or attention deficiency.
• In addition, the test can also diagnose brain related and neuro-psychological disorder.
Point to remember:
The WISC system is not useful to determine the extreme form of intelligence like IQ below 40 and above 160. Wechsler himself focused on this point many times that test is not adequate for children with IQs of below 70 or above 130. Despite of this fact, people use this test to determine the intelligence of deferentially able children who usually have IQ above 130 that is not very appropriate thing.
<em>Note:</em><em> This answer is very generic based on the statement of the question. If you have some specific options of the questions, please post it again with them or comment. Thank you.</em>
Answer:
a, b-colliding, d -high energy
