Answer:
1. d. changes in the methylation patterns of <em>loci</em> involved in growth and metabolic disease
2. b. differences in the expression of metabolic genes
d. changes in histone acetylation patterns
Explanation:
Epigenetics refers to the study of heritable changes in gene expression which are not dependent on DNA sequence. Epigenetic mechanisms involve DNA methylation, histone modifications (acetylation, methylation, phosphorylation, etc) and regulatory non-coding RNA (ncRNA) pathways. These epigenetic mechanisms work together and mutually reinforce each other in order to modulate gene expression (either by activating or suppressing gene expression). In consequence, transcriptome data (e.g., genes differentially expressed in particular tissues/cells or stages of development) is an important piece of evidence indicating the existence of epigenetic modulation.
Answer:
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