<span>Some mutations don't have any noticeable effect on the phenotype of an organism. This can happen in many situations: perhaps the mutation occurs in a stretch of DNA with no function, or perhaps the mutation occurs in a protein-coding region, but ends up not affecting the amino acid sequence of the protein</span>
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The answer is A
no its really just A like the first answer
man its hard to explain stuff
Answer:
C-able to relieve haemophilia
Explanation:
Factor V111 is a blood clotting factor;produced in the liver and body endothelial cells. It is usually exist as inactive form beacuse it is binded to glycoprotein (glycogen +protein) called Von Willebrand factor when released into the blood stream.
If absent in the gene of certain individuals due to mutations, it result in a sex-linked conndtion called haemophilia, where blood failed to clot when blood vessels are damaged leading to profuse bleeding/ hemorrhage.
Ideally in a normal individuals the inactive from of factor VIII are continuously circulated in inactive forms in the blood stream, until a damaged blood vessels occurs. At the injured site they are converted to active from called coagulating factor VIIIa,,by separation from Willebrand factor, react with coagulating factor IX to initiate clotting. The factor VIII is a co- factor for factor IX, and together with calcium ion,phospholipids converts t to factor IXa,
The latter converts prothrombin to thrombin. The thrombin convert fibrinogen to fibrin, which form a stable fibrin clot at the injured site to arrest bleeding.<u> </u><u>The cascade of events is lacking individual without factor VIII. Therefore bleeding occurs.
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Consequently, symptoms of hemophilia can be relieved by a functional factor VIII, because it will prevent the deficiency in factor VIII in the affected individuals by acting as co-factors for the conversion of factor IX to IXa, to initiate clotting.
