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Nadya [2.5K]
3 years ago
12

Explain the four steps of Pharmacokinetic.

Health
2 answers:
harina [27]3 years ago
5 0

Answer:

absorption, distribution, excretion &metabolism

Explanation:

<em>Absor</em><em>ption</em><em> </em><em>is</em><em> </em><em>the</em><em> </em><em>process</em><em> </em><em>by</em><em> </em><em>which</em><em> </em><em>drugs</em><em> </em><em>entre</em><em> </em><em>the </em><em>body</em><em>.</em><em> </em><em>given</em><em> </em><em>by</em><em> </em><em>any </em><em>route</em><em> </em><em>other </em><em>than</em><em> </em><em>intraven</em><em>ously</em><em>,</em><em> </em><em>drugs </em><em>molecules </em><em>must</em><em> </em><em>cross</em><em> </em><em>tissue</em><em> </em><em>membranes </em><em>to</em><em> </em><em>enter</em><em> </em><em>the</em><em> </em><em>brain</em><em> </em><em>(</em><em>ig</em><em>)</em>

<em>distributio</em><em>n</em><em> </em><em>is</em><em> </em><em>the</em><em> </em><em>process</em><em> </em><em>by</em><em> </em><em>which </em><em>drugs </em><em>move</em><em> </em><em>around </em><em>the</em><em> </em><em>body</em><em> </em><em>after</em><em> </em><em>ente</em><em>ring</em><em> </em><em>the</em><em> </em><em>blood</em><em>,</em><em>drug</em><em> </em><em>molecu</em><em>les</em><em> </em><em>must </em><em>cross</em><em> </em><em>capillary</em><em> </em><em>walls</em><em> </em><em>to </em><em>enter</em><em> </em><em>the</em><em> </em><em>tissues</em><em> </em><em>,</em><em> </em><em>reach</em><em> </em><em>cell</em><em> </em><em>mem</em><em>branes</em><em> </em><em>and</em><em> </em><em>enter</em><em> </em><em>cells</em>

<em>Metab</em><em>olism</em><em> </em><em>is</em><em> </em><em>the</em><em> </em><em>process</em><em> </em><em>by</em><em> </em><em>which </em><em>drugs</em><em> </em><em>are</em><em> </em><em>chemically</em><em> </em><em>altered</em><em> </em><em>to</em><em> </em><em>make</em><em> </em><em>them</em><em> </em><em>suffici</em><em>ently</em><em> </em><em>water</em><em> </em><em>soluble</em><em> </em><em>for</em><em> </em><em>excretion</em><em> </em><em>in</em><em> </em><em>urine</em><em> </em><em>or</em><em> </em><em>faces</em><em>.</em><em> </em><em>metabo</em><em>lism</em><em> </em><em>occurs </em><em>in</em><em> </em><em>a</em><em> </em><em>variety</em><em> </em><em>of</em><em> </em><em>body</em><em> </em><em>organs</em><em> </em><em>and</em><em> </em><em>tissues</em><em>,</em><em> </em><em>but</em><em> </em><em>chiefly </em><em>in</em><em> </em><em>the </em><em>liver</em><em>,</em><em>gut</em><em> </em><em>wall</em><em> </em><em>,</em><em> </em><em>kidney </em><em>and</em><em> </em><em>skin</em><em> </em>

<em>Excre</em><em>tion</em><em> </em><em>is</em><em> </em><em>the </em><em>process</em><em> </em><em>by</em><em> </em><em>which</em><em> </em><em>drugs</em><em> </em><em>leave</em><em> </em><em>the</em><em> </em><em>body</em><em>.</em><em> </em><em>drugs</em><em> </em><em>that</em><em> </em><em>are</em><em> </em><em>suffi</em><em>ciently</em><em> </em><em>water</em><em> </em><em>so</em><em>luble</em><em> </em><em>will</em><em> </em><em>be</em><em> </em><em>excreted</em><em> </em><em>unchange</em><em>d</em><em> </em><em>in</em><em> </em><em>the </em><em>urine</em><em>.</em><em> </em><em>lipid-soluble</em><em> </em><em>drugs</em><em> </em><em>must</em><em> </em><em>be </em><em>modi</em><em>fied</em><em> </em><em>to </em><em>water</em><em> </em><em>sol</em><em>uble</em><em> </em><em>matabolitres</em><em> </em><em>be</em><em>f</em><em>o</em><em>r</em><em>e</em><em> </em><em>excretion </em><em>via</em><em> </em><em>the</em><em> </em><em>ki</em><em>d</em><em>n</em><em>e</em><em>y</em><em> </em><em>or</em><em> </em><em>into</em><em> </em><em>the</em><em> </em><em>intestine</em><em> </em><em>via</em><em> </em><em>bile</em>

Oxana [17]3 years ago
3 0

Answer:

The main processes involved in pharmacokinetics are absorption, distribution, and the two routes of drug elimination, metabolism and excretion. Together they are sometimes known by the acronym 'ADME'.

Explanation:

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