The answer to the question above is CYTOPLASM. This is the part of the cell wherein the pigment, bilirubin, can accumulate. Bilirubin is actually one of the major components of bile along with bile acids. The manifestation of jaundice means that there is a retention of bilirubin. This pigmentation can then be accumulated at the cytoplasm. The cytoplasm is the part of the cell which comprises the more specific parts that are outside of the nucleus.
Vertebrates, and a few invertebrates, have a closed circulatory system. Closed circulatory systems have the blood closed at all times within vessels of different size and wall thickness. In this type of system, blood is pumped by a heart through vessels, and does not normally fill body cavities.
Every cell in your body has the same genes/DNA but, the gene expression process decides which genes are active in which cells which is how each cell type gets it properties.
