Answer:
The reason for the offspring to present these genotypes is that during the formation of the gametes, the alleles separate and are inherited independently, therefore they can generate several different phenotypic combinations.
Explanation:
In order for an offspring to present very different phenotypes, as shown in the question above, it is necessary that the two red griffins with blue eyes that were crossed are heterozygous. Thus it will be possible for the offspring to present a wide variety of phenotype, according to Mendel's second law.
Mendel's second law is called the Law of segregation. This law explains that the alleles (which determine the characteristics of individuals) are separated in the formation of gametes and inherited by the offspring of a cross independently, and can generate different combinations of phenotypes, when the parents of a cross are heterozygous.
By the late 1830s, botanist Matthias Schleiden and zoologist Theodor Schwann were studying tissues and proposed the unified cell theory. The unified cell theory states that: all living things are composed of one or more cells; the cell is the basic unit of life; and new cells arise from existing cells.
The pKa represents the pH of the medium at which the zwitterionic amino acid assumes most stable ionic form due to structural stabilization. As the pKa is dependent upon the environmental factors of the solution around the amino acids, a change in their structure and localization can cause change in the pKa of the protein. Thus, the answers can be found as below:
Part A: Decrease (As the lysine is basic in nature, it will tend to stabilize the electrostatic interaction and weak interactions between the acidic amino acids and hydrogen bonds in the viscinity, thus lowering the pH and hence pKa of the protein)
Part B: Increase (As the carboxyl group is acidic in nature, removal of it will tend to increase the pKa since the basic amino acids will tend to accumulate more negative charge in their viscinity)
Part C: Increase (As glutamic acid is an acidic amino acid, its shift from outside to a non-polar site will prevents its ionization and hence the pKa will tend to shift from slightly acidic to slightly basic, hence increase)
The clinical manifestations should the nurse expect are reports of leg fatigue, tortuous veins in the legs and pain in lower extremities when standing.
In addition, leg fatigue is a communal clinical manifestation triggered by venous stasis and insufficient tissue oxygenation. The vein walls deteriorate and dilate causing distended, bulging veins that look tortuous and darkened. As vein walls weaken and dilate venous pressure increases and the valves turn out to be useless in which vein stasis and inadequate oxygenation end result is limb discomfort. The discolored toenails effect from a fungus below the nail or chronic hypoxia, not varicose veins, confined to a small area of heat in a calf is a mark of thrombophlebitis and reddened zones on a leg are symptomatic of thrombophlebitis.
