Answer:
Tamoxifen is an irreversible, competitive inhibitor.
Explanation:
In order to binds to the active site of the estrogen receptor protein, tamoxifen have to compete with the other chemical compound, and inhibits the estrogen release, so it is a competitive inhibitor. Then, you said that when tamoxifen binds to the receptor, the protein is permanently deactivated, so it is also irreversible.
Answer:
by statistical analyses, especially by determining the p-value
Explanation:
In general, observations and results obtained from experimental procedures are subjected to a statistical test to check the robustness of the working hypothesis. The p-value is the most widely used statistical index in order to test such observations and results. The p-value is the statistical probability of obtaining extreme observed results when the null hypothesis is considered correct. A p-value lesser than 0.05 generally is considered statistically significant and then the null hypothesis can be rejected. In consequence, a very low p-value (which is obtained by statistical analysis of the observations and results), indicates that there is strong evidence in support of the alternative hypothesis.
