Vibrio cholerae produces a toxin that binds to a plasma membrane receptor on intestinal cells of the host. The toxin permanently
activates the G protein in target cells, causing them to lose water rapidly. When a person is infected with cholera they suffer severe dehydration.The V. cholerae toxin disrupts homeostasis in humans by ___________.
causing severe diarrhea and water loss in affected cells and surrounding tissues
damaging skin cells leading to external erosion and ulceration
superficial dehydration through direct drying of intestinal tissues
killing intestinal cells and leading to rapid replacement via mitosis
causing severe diarrhea and water loss in affected cells and surrounding tissues
damaging skin cells leading to external erosion and ulceration
superficial dehydration through direct drying of intestinal tissues
killing intestinal cells and leading to rapid replacement via mitosis
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Answer:
The cell's proteins are first manufactured in the ribosomes. The polypeptide chains then enter the lumen of the Rough Endoplasmic Reticulum where they are properly folded with the help of chaperones and modified to achieve their desired shape which relates to their function. The proteins also undergo quality control in the RER, These proteins are then transported by vesicles, budding out of the trans side of the RER, and transported to the cis side of the Golgi apparatus. In the Golgi bodies, the proteins undergo further post-translational modification and packaging. Vesicles carrying the final proteins then bud off of the trans side of the Golgi apparatus and transport the protein to the cell membrane where they secreted them.
