Lianne's is correlated with "Poor health and higher death rates".
<u>Explanation</u>:
Social isolation is a state where a person isolates himself completely from the society and the people even his near ones, completely. When a person does that he starts to feel lonely and lazy which results in captivating negative energy. Due to this, he incorporates bad habits such as smoking, drinking, sometimes taking drugs, and having an imbalanced diet which ends up with degradation of one's health. These habits increase the death rate because they may suffer from chronological diseases.
The Chinese, however, did put in place some measure of border closure in the 15th century in reaction to an influx of foreign merchants and settlers and in order to protect local traditions. The isolation of the empire started during the Ming dynasty and continued into Qing dynasty.