Agriscience is the right answer :)
        
                    
             
        
        
        
José probably doesn't feel any pain because his body, during and after exercise released endorphins which are endogenous opioids. This endorphins promote a sense of satisfaction and pleasure, and make pain and discomfort feel irrelevant.
        
             
        
        
        
For the answer to the question above, I believe the answer is that the bones get or have a greater risk for bone fracture <span>if calcium is not replaced in bone tissue. The bones could become more brittle. For women, they can suffer from Osteoporosis. </span>