Answer:
The correct option is: <em>a deficiency of dopamine in the substantia nigra.</em>
Explanation:
The substantia nigra is the principal site involved in the physiopathology of Parkinson´s disease.
Cells from this area degenerate and die progressively causing important degeneration in the central nervous system. The cells that die -with no known reason- are those that produce dopamine and proportionate dopaminergic innervation to the encephalon. In fact, almost all the symptoms exhibited by patients with the disease can be explained by the lack of dopamine in the substantia nigra.
This area uses the neurotransmitter to communicate neurons from the base ganglia. Ganglia are responsible of modulating and modifying movements.
The nigrostriatal system participates in planning and automatic execution of learned movements. When the ganglia activity decreases, so it does the amount and velocity of movements, something typical of the disease.
Answer:
Genotype ratio 1:1, there are two types of genotype BB and Bb in equal ratio.
Phenotype ratio 1:0, because all offspring have allele B. “B” is dominant and there is no bb genotype, so recessive trait will not be shown.
Explanation:
Answer:
Cystic fibrosis mutation is recessive to normal allele because only one functional or normal allele is enough to produce a functional protein. So, if mutation is present in one allele then also, a normal protein can be made from normal allele. The presence of normal protein prevents the expression of disease.
In addition, mutated allele only results in the loss of function of protein which can be compensated by the expression of normal allele. It does not add any toxic effect to the protein. Consequently, the disease is inherited in autosomal recessive fashion.
In contrast, Huntington mutation not only alters the structure of the functional protein but also adds toxicity to it. The altered protein is enable to interact with 100s of other proteins and inhibit or decrease their function. So, if only one allele is present then also, the mutated protein will be produced and it will result in the phenotype. Consequently, it is inherited as autosomal dominant fashion.
Answer: A) Increased GI mobility
Explanation: They sympathetic nervous system inhibits the activity if the stomach, therefore, GI mobility decreases and does not increase. The parasympathetic nervous system is the one that increases the GI mobility.
Answer: We need DNA to reproduce and it's unique due in part to recombination. recombination is traded between the chromosomes that make up a pair.
Explanation:
