Question

Monamine oxidase inhibitors (MAO inhibitors) Select one: a. prevent synaptic transmission. b. enhance the breakdown of norepinephrine. c. enhance the binding of norepinephrine to its receptors. d. prevent the release of norepinephrine by the presynaptic terminal. e. have no effect on the action of norepinephrine.

Answer 1

Answer:

The correct answer is c. "enhance the binding of norepinephrine to its receptors".

Explanation:

Monamine oxidase inhibitors (MAO inhibitors) were the first antidepressant drugs to be developed and cause the accumulation of norepinephrine, dopamine, and serotonin. MAO inhibitors function by inhibiting the activity of enzymes that broke down these compounds. The accumulation of norepinephrine enhance the binding of norepinephrine to its receptors, allowing for a higher effect of norepinephrine.