Breathing in air pollutants can irritate your airways. It may cause shortness of breath, coughing, wheezing, asthma episodes and chest pain. Overtime, exposure to air pollution puts you at risk for lung cancer, heart attack/strokes, etc. Some people are more at risks from others though
When there is myelosuppression, the suggestive finding is
there is a decrease in the platelets and red blood cells. Also called the bone
marrow suppression, myelosuppression is a common side effect of the treatment
of chemotherapy. When this side effect happens, there is a decrease in the production
of blood cells. The result which may be the effect of myelosuppression is a
decrease in one, two or all three types of blood cells. Most patients of
chemotherapy experience a decrease in red blood cells. Another effect is the
decrease of white blood cells by most patients. Myelosuppression will be
subcategorized as neutropenia when chemotherapy results to the reduction of
neutrophils which is a specific type of white blood cells. Thrombocytopenia is
the term for a drop in platelet numbers. This kind of suppression is not that common. Only 10 percent of cancer patients undergo
the negative effects of this kind of suppression.
Answer:
Answer explained
Explanation:
a. Overexpression of Axl receptor tyroxine kinase correlates with the decresed patient's overall survival and hence it's inhibition is under process.
AXL TKI BMS777607 treatment increased AXL protein levels after 24 h as observed by Western blot and flow cytometry analysis. Mechanistically, this inhibition-induced AXL cell surface accumulation was neither associated with epigenetic modifications, nor altered transcriptional and translational regulation. Hence this later increased the glycosylated protien abundance in kinase dead mutant. The kinase function blockaging resulted in impaired internalisation which finally incresed the level of proliferation.
An alternative technique may exist in linkage of Axl Tkl to a degradation machinery recruitment unit .
b. Mendelian disorders like cystic fibrosis results from error in the given DNA sequence which can be autosomal dominant and recessive both and also X or Y linked. Mutated gene results in the Mendelian disorders. Whereas in cancer there can be mutation or proliferation of the given cells in a specific area. In cancer cells there is 2.5 times more the mRNA present while 6.2times the DNA and hence the detection and diagnosis automatically becomes difficult as in Mendelian disorders only single sequence needs to be studied at a time .
Most macromolecules are polymers<span>, which are long chains of subunits called </span>monomers<span>. ... of </span>polymers<span> (and </span>living things<span> in general) there are only about 40 - 50 common </span>monomers<span>. ... Polysaccharides may be </span>made<span> from thousands of simple sugars </span>linked<span> together. ... Cellulose is a polysaccharide </span>produced<span> by plants.</span>
