Answer:
Answer explained
Explanation:
a. Overexpression of Axl receptor tyroxine kinase correlates with the decresed patient's overall survival and hence it's inhibition is under process.
AXL TKI BMS777607 treatment increased AXL protein levels after 24 h as observed by Western blot and flow cytometry analysis. Mechanistically, this inhibition-induced AXL cell surface accumulation was neither associated with epigenetic modifications, nor altered transcriptional and translational regulation. Hence this later increased the glycosylated protien abundance in kinase dead mutant. The kinase function blockaging resulted in impaired internalisation which finally incresed the level of proliferation.
An alternative technique may exist in linkage of Axl Tkl to a degradation machinery recruitment unit .
b. Mendelian disorders like cystic fibrosis results from error in the given DNA sequence which can be autosomal dominant and recessive both and also X or Y linked. Mutated gene results in the Mendelian disorders. Whereas in cancer there can be mutation or proliferation of the given cells in a specific area. In cancer cells there is 2.5 times more the mRNA present while 6.2times the DNA and hence the detection and diagnosis automatically becomes difficult as in Mendelian disorders only single sequence needs to be studied at a time .
Answer:
we can't answer there are not following
<span>A physical system is best characterized as a collection of MATTER THAT HAS DISTINCT BOUNDARIES.
</span><span>How does this phenomenon validate the Law of Conservation of Energy?
</span><span>The light energy travels through the water until it is reflected or absorbed.
</span><span>What conditions would most likely be present in this region?
Organisms growing on bare rock
</span><span>What is the best explanation based on these observations?
</span><span>Lobsters are adapting to cooler temperatures.
</span><span>- Ideal water temperature for lobster is around 53-64 degrees Fahrenheit. With the exceedingly warm waters (68 degrees Fahrenheit), lobsters are forced to move to the north where the temperature is ideal for their life cycles.</span>
Actually yes. You can find organisms, like bacteria, living in deep oceans, which do not have access to sunlight. There are cases in which they use thermal resources in order to produce energy. They are called <span>chemoautotrophs. You can find them around deep ocean "smokers".</span><span />
Answer:
The most common elements, like carbon and nitrogen, are created in the cores of most stars, fused from lighter elements like hydrogen and helium. The heaviest elements, like iron, however, are only formed in the massive stars which end their lives in supernova explosions.
Explanation:
