Cellular respiration that proceeds without oxygen is called anaerobicrespiration. Then, about 2 or 3 billion years ago, oxygen was gradually added to the atmosphere by early photosynthetic bacteria. After that, living things could use oxygen to break down glucose and make ATP.
An inversion occurs when a chromosome breaks in two places; the resulting piece of DNA is reversed and re-inserted into the chromosome. Genetic material may or may not be lost as a result of the chromosome breaks.