With out any options to chose from,
the best answer would be
...to greatly extend the numbers and range of patients who could benefit from transplants, and to provide cell replacement therapy to treat debilitating diseases
If the pH is too low in the stomach, it will denature the proteins that usually break down food. The major enzyme in the stomach is pepsin, which breaks down proteins in the food we eat. Therefore, the answer is the second statement, "Decrease in pH of the stomach will distort the active site of the enzyme pepsin, which affects its action." Hope this helps! :)
The persuasive technique he uses is anticipation.
They believed this because the continents appear to have once been fitted together and it was called pangaea