The correct answer would be "increased body temperature".
The homeostasis refers to the ability of the body to maintain a stable internal environment irrespective of the change in the external environment.
For example, running causes an increase in body temperature as heat or energy, carbon dioxide, and water are produced by cellular respiration. This increase in body temperature activates the sweating of the body.
The sweating with the help of evaporation reduces the elevated body temperature to the normal range.
Thus, homeostasis of body temperature is maintained.
The endoplasmic reticulum is like the highway system because the cell uses the endoplasmic reticulum to move material throughout the cell like people use highways to move throughout the country.
I would go with It will increase the reactivity with the substrates. Because if there is no factors, the <span>rate of enzyme activity will increase. </span> Hoped I helped :)