Q = recessive allele frequency = 0.3, and thus in H-W equilibrium there are ONLY two alleles, q (recessive) and
p (dominant). Therefore all of the p and q present for this gene in a population must account for 100% of this gene's alleles. And 100% = 1.00.
So p, the dominant allele frequency, must be equal to 1 - q --> p = 1 - q
p = 1 - 0.3 = 0.7.
Since heterozygotes are a combination of the p and q, we must again look at the frequencies of each genotype: p + q = 1, then (p+q)^2 = 1^2
So multiplying out (p+q)(p+q) = 1, we get: p^2+2pq+q^2 = 1 (all genotypes), where p^2 = frequency of homozygous dominant individuals, 2pq = frequency of heterozygous individuals, and q^2 = frequency of homozygous recessive individuals.
Therefore if the population is in H-W equilibrium, then the expected frequency of heterozygous individuals = 2pq = 2(0.7)(0.3)
2pq = 2(0.21) = 0.42, or 42% of the population.
Hope that helps you to understand how to solve population genetics problems!
Competitive inhibition vs allosteric inhibition
In competitive the substrate and inhibitor bind at the same active site - pretty straightforward. In allosteric regulation (speaking specifically about inhibition here), the inhibitor is binding at a site other than the active site, and changing the enzyme in some way to make it inactive.
Answer:
The mother can carry a full-term baby with A blood type because the mother's blood does not mix with the baby's blood, so the mother's immune system does not activate attacking the baby.
Explanation:
The reason why a mother with B blood type and A antibodies in her system can carry a full-term pregnancy is thanks to the placenta. The placenta is a shared organ between the mother and the baby. Its function is to protect the baby and produce the necessary exchanges of nutrients and wastes between the maternal blood and the baby's blood. As the two types of blood are separated, and they never get in contact during pregnancy, the immune system of the mother does not recognize the baby as a treat. The mother can have A antibodies in her plasma due to a previous pregnancy where during delivery, the two types of blood mixed, also it can be due to any contact with the A blood type. When the foreign blood enters the body, the immune system forms antibodies for it.
The substrate and the active site both need to fit together perfectly in order for the enzyme to work properly. If their shape is changed, typically through heat or a change in pH, the enzyme will not work.
