Glucocorticoids are hormones of the family of corticosteroids that participate in the regulation of carbohydrate metabolism favoring gluconeogenesis and glycogenolysis; They also have immunosuppressive activity. Its regulatory action also extends to the intermediate metabolism of fats and proteins. Glucocorticoids are mainly produced in the adrenal cortex of humans and are cortisol, cortisone and corticosterone. Cortisol is the most important glucocorticoid in humans.
From the pharmacological point of view they are corticosteroids for systemic use whose reference drug is hydrocortisone, which at high concentrations can suppress the production of ACTH adrenocorticotropic hormone in the adenohypophysis.
