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Answer:
Drug-drug interactions (DDIs) are one of the commonest causes of medication error in developed countries, particularly in the elderly due to poly-therapy, with a prevalence of 20-40%. In particular, poly-therapy increases the complexity of therapeutic management and thereby the risk of clinically important DDIs, which can both induce the development of adverse drug reactions or reduce the clinical efficacy. DDIs can be classify into two main groups: pharmacokinetic and pharmacodynamic. In this review, using Medline, PubMed, Embase, Cochrane library and Reference lists we searched articles published until June 30 2012, and we described the mechanism of pharmacokinetic DDIs focusing the interest on their clinical implications.
Keywords: Absorption, adverse drug reaction, distribution, drug-drug interactions, excretion, metabolism, poly-therapy
A. late diagnosis is the right answer
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If the infant stops responding, position them on a firm, flat surface, and yell for help. Check for breathing and begin CPR. After 15 compressions, open the airway and look for a foreign object. If visible, remove it and attempt to ventilate with two breaths.
Stimulants and depressants have an effect on the synapses among neurons in the frightened system:
- stimulants purpose greater neurotransmitter molecules to diffuse throughout the synapse.
- depressants stop the next neurone sending nerve impulses.
Psychotropic drugs exert their outcomes by changing a synaptic occasion. these alterations in the end change the pastime of a neurotransmitter. some psychotropic drugs facilitate the effects of a neurotransmitter, and are referred to as agonistic.
Tablets make their effects regarded via performing to beautify or intervene with the interest of neurotransmitters and receptors in the synapses of the mind. some neurotransmitters carry inhibitory messages across the synapses, at the same time as others bring excitatory messages.
Amphetamine, heroin, marijuana, nicotine, alcohol, and prescription painkillers, can regulate a person's conduct by way of interfering with neurotransmitters and the regular communique between brain cells.
Learn more about drugs here: brainly.com/question/15746818
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