<span>B.his centralization of the first unified empire in India </span>
Answer:
the answer is C Andrew Jackson opposed the removal of Indians.
For his work on the Missouri Compromise, Senator Henry Clay became known as the “Great Pacificator." ... It was repealed by the Kansas-Nebraska Act of 1854, which established popular sovereignty (local choice) regarding slavery in Kansas and Nebraska, though both were north of the compromise line.
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Native peoples of America had no immunity to the diseases that European explorers and colonists brought with them. Diseases such as smallpox, influenza, measles, and even chicken pox proved deadly to American Indians. Europeans were used to these diseases, but Indian people had no resistance to them.