In lecture we discussed two aspects of the critical concentration. What is the relationship between the critical concentration a
nd whether or not actin filaments will form in a reaction? What is the relationship between critical concentration and reaction that contains f-actin at steady state?
Once the steady-state phase is reached, the equilibrium concentration of the pool of unassembled subunits is called the critical concentration (Cc). This parameter is a measure of the ability of a solution of G-actin to polymerize. Under typical in vitro conditions, the Cc of G-actin is 0.1 μM.
