The combination of depressants and alcohol can multiply the effects of the drug and alcohol. Alcohol is considered a depressant and the combination can block other neurotransmitters, resulting in a state of increase intoxication.
The correct answer is C. Mood disorder or personality disorder.
Michael is not displaying any behavior that would be symptomatic of a psychotic disorder, eating disorder or impulse disorder. Sadness and refusing to socialize can be attributed to mood disorders such as depression and generalized anxiety disorder and personality disorders such as borderline personality disorder.