Fatty acid biosynthesis is the formation of fatty acid from NADPH acetyl CoA with the help of the fatty acid synthases enzyme. For the biosynthesis of fatty acid, NADPH is an essential substrate that comes from the conversion of glucose-6- P into ribulose-5-phosphate in the pentose phosphate pathway.
The other source of the NADPH is by the conversion of the citrate into the pyruvate in the cytosol of the cell.
