defence cell in blood are called white blood cells
Answer:
DO support the person's breathing by administering oxygen or performing rescue breathing. DO administer naloxone. DO put the person in the “recovery position” on the side, if he or she is breathing independently. DO stay with the person and keep him/her warm.
Explanation:
A product which contains magnesium and an amino acid, L-theanine as key ingredients.
- Magnesium included in the dietary supplement is A vitamin and is need for health.
Magnesium is a mineral that contributes to proper body functioning and proper sleep. Our body can't make Magnesium, so we need to take it from our diet.
For more information on magnesium, visit
brainly.com/subject/chemistry
Answer:
Okay
Explanation:
Human topoisomerase I plays an important role in removing positive DNA supercoils that accumulate ahead of replication forks. It also is the target for camptothecin-based anticancer drugs that act by increasing levels of topoisomerase I-mediated DNA scission. Evidence suggests that cleavage events most likely to generate permanent genomic damage are those that occur ahead of DNA tracking systems. Therefore, it is important to characterize the ability of topoisomerase I to cleave positively supercoiled DNA. Results confirm that the human enzyme maintains higher levels of cleavage with positively as opposed to negatively supercoiled substrates in the absence or presence of anticancer drugs. Enhanced drug efficacy on positively supercoiled DNA is due primarily to an increase in baseline levels of cleavage. Sites of topoisomerase I-mediated DNA cleavage do not appear to be affected by supercoil geometry. However, rates of ligation are slower with positively supercoiled substrates. Finally, intercalators enhance topoisomerase I-mediated cleavage of negatively supercoiled substrates but not positively supercoiled or linear DNA. We suggest that these compounds act by altering the perceived topological state of the double helix, making underwound DNA appear to be overwound to the enzyme, and propose that these compounds be referred to as ‘topological poisons of topoisomerase I’
