In the case of chronic bronchitis or chronic inflammation of the airways, cyanosis or the bluish discoloration of the skin results from the reduced levels of oxygen in the blood. With reduced oxygen levels, the blood in the arteries will not be bright red in color but rather be brownish just like venous blood and this reflects in the skin as bluish in color.
I will choose : Malaria.
Malaria is an infectious disease caused by a parasite of the genus Plasmodium (the most predominant is the falciparum species), spread by the bite of certain species of anopheles mosquitoes. The malaria parasite is mainly transmitted, at night, during the bite by a female mosquito of the genus Anopheles, itself contaminated after stinging an individual with malaria. The parasite infects the victim's liver cells and then circulates in the blood, colonizing the red blood cells and destroying them.
The symptoms are: generalized fatigue, loss of appetite, dizziness, headache, digestive disorders (gastric embarrassment), nausea, vomiting, abdominal pain, diarrhea and diffuse myalgia.
Their mitochondria do not have an electron trasnport chain and so cannot funciton in aerobic respiration.
Electron Transport Chain (ETC) essentially makes the energy required for respiration.
Hope this helps
