Well I have personal experience with this. I had chronic pain for a long time and I couldn't go anywhere. I couldn't go to see my friends or to go outside and enjoy anything because I was in constant pain. Eventually, I had depression due to lack of joy in my life and lack of going outside. If you are stuck with physical pain and it causes you to be non-mobile, then you are going to have mental and social issues. Hope this helps :)
Answer:
Blood enters the heart through two large veins, the inferior and superior vena cava, emptying oxygen-poor blood from the body into the right atrium of the heart. As the ventricle contracts, blood leaves the heart through the pulmonic valve, into the pulmonary artery and to the lungs where it is oxygenated.
The regulatory system given to this particular question would be Homeostasis. homeostasis means that it creates a balance between things that are interdependent upon each other.