Answer:
The correct answer would be "T-lymphocytes would bind self-antigens".
Negative selection of T-lymphocytes takes place in the cortico-medullary junction in the thymus.
It removes T-lymphocytes which show high-affinity binding with self-antigen. Thus, it helps in introducing self-tolerance in T-lymphocytes.
In absence of negative selection, T-lymphocytes which show high-affinity binding for self-antigen would survive and develop into mature T-lymphocytes.
Consequently, T-lymphocytes would able to bind to self-antigens of the body which can result in autoimmune disease.
