Question

Many proteins interact with DNA at physiological pH because ________. a. Proteins are naturally attracted to DNA regardless of the pH b. Proteins and DNA interact using mainly hydrophobic interactions c. The positively charged DNA is electrostatically attracted to negatively charged regions on proteins d. The negatively charged DNA is electrostatically attracted to positively charged regions on proteins

Answer 1

Answer: Option D) The negatively charged DNA is electrostatically attracted to positively charged regions on proteins

Explanation:

Proteins are composed of several amino acids with positively charged amino groups in their side chain, while DNA is composed of several nucleotides with negatively charged phosphate groups.

Thus, there is an electrostatic attraction of negatively charged DNA to positively charged regions on proteins at physiological pH.

Answer 2

Many proteins interact with DNA at physiological pH because the negatively charged DNA is electrostatically attracted to positively charged regions on proteins.