Giraffes and Elephants: Giraffes have adapted a long neck over time letting them eat and access food allowing them to survive. If a dry season was unusually long they would succeed fine because they are able to eat and drink from the trees. Elephants have survived with similar tactics of eating higher up, they have rough skin allowing them to outlast the heat, and only need water after long periods of time.
Lisbon Portugal has had one of the worst
Answer: Denaturing
Explanation: Enzymes are made of amino acids that are linked by bonds, amongst those bonds are hydrogen bonds that are very weak. High temperatures and low pH(acidity) breaks those bonds changing the molecular conformation of the enzymes. That way they denature and loss the ability to perform their functions. High temperatures and acidity alter the structure of their active site preventing the substrate from binding to them. While high temperatures denatures enzymes, low temperature renders them inactive.