Some of the factors are:
<span>-Moderate climate.
-central geography,
-ease of transportation,
-highways,
-railroads,
-location near a large body of water
</span>Large cities tend to develop far from cities that had either too hot or too cold temperature. It also must be easily accessible by other regions and provide the people with necessary resources that help them sustain their living (such as water, food crops, woods, etc)
Answer:
For chemical reactions where the free energy of the reactants is much greater than the free energy of the products (DGo' < 0), the reaction proceeds spontaneously and the net result is a large ratio of product to reactant (large Keq).
Explanation:
It is true they do have internal fertilization. This is also one of the reason why it is easy to differentiate between a male or a female shark on birth due ot internal fertilization. <span />