The cell cycle is controlled by many cell cycle control factors, namely cyclins, cyclin-dependent kinases (Cdks) and cyclin-dependent kinase inhibitors (CKIs). Cyclins and Cdks, which are positive regulators of the cell cycle, activate cell cycle factors that are essential for the start of the next cell cycle phase.
A :-) Sickle cell disease occurs more often among people from parts of the world where malaria is or was common. It is believed that people who carry the sickle cell trait are less likely to have severe forms of malaria.
