In eukaryotic cells the DNA can be found in the nucleus mainly. so DNA replication takes place in the nucleus during the S phase of the cell cycle.
Also in eukaryotic cells there are mitochondria and chloroplasts (plants) and these have circular DNA and they also get replicated (according to their own mechanism).
Prokaryotic cells don't contain a nucleus. They do not contain DNA in the cytoplasm and thus the DNA replication will take place here.
I really hope this helps!
They say how an enzyme perfectly fits into its substrate is alike a "lock and key".
Only one specific enzyme can fit a specific substrate.
Through leaching. B horizons or subsoil get materials from above through accumulated rain water that leached these materials and precipitated it into the B horizon.