Hemophilia is the result of a defective X chromosome. males have XY chromosomes; females have XX chromosomes. If a man has a defective X chromosome, he has no normal X chromosome to balance it out. Therefore, he is more likely to present hemophilia. However, a hemophiliac man's male children will all be healthy, assuming his partner is not a hemophiliac, because the defective X chromosome was not passed on. All his daughters will be carriers, though, regardless of whether their mother is a hemophiliac.
3, 2, 4, 1
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You didn't give the options for "which" but I assume your multiple choice questions will all be environmental factors that can cause mutations. To pass on to offspring, any mutation in the gametes or a chromosome may cause a mutation in the offspring.
