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Vlad [161]
3 years ago
7

Taxol is an anticancer drug extracted from the pacific yew tree that binds to microtubules and prevents their depolymerization.

Actively dividing cells treated with taxol become blocked in which phase of mitosis?
Biology
1 answer:
Illusion [34]3 years ago
6 0

Answer and Explanation:

Taxol is a type of chemotherapeutic drug that is anti-mitotic against cancerous cells which are actively dividing. At high concentration, it causes mitotic arrest at G2/M phase whereas at low concentration, apoptosis is induced at G0 and G1/S phase through activation of p53 depending on the dose concentration. It blocks the cell cycle by stabilizing the microtubule cytoskeleton against depolymerization. P53 is a type of tumor suppressor gene that is activated to inhibit the excessive proliferation of cancer cells.

Tumour suppressor genes code for proteins that slow down cell growth. They can halt the cell growth and division by linking the cell cycle to DNA damage or repression of genes essential to cell cycle.

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Answer:

Sickle cell disease in an autosomal recessive inherited disease which is caused by the mutation in the HBB (hemoglobin-β gene) gene present on the chromosome no. 11. In sickle cell, the red blood cells become sickle shape due to the abnormal shape of hemoglobin present in it.

These sickle cells are known to form a blockage in the blood vessels thereby causing damage to the vital organs. Human spleen constantly destroys sickle cells because they get trapped in it which causes a disease called sickle cell anemia.

Sickle cell anemia is normally the problem in genetic disease which is inherited from the parents to children. When both the DNA strand has a mutation in their HBB gene then only this disease will affect the individual.  

8 0
3 years ago
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7 0
3 years ago
Flea
stepladder [879]

Answer:

all of them are.

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