Mendel took precautions to avoid contamination by pollen through self pollination of the P generation. He controlled the fertilization processes between the plants. He self pollinated the first pureline varieties to form the P generation. He then cross pollinated them to get F1 generation. Every step of his experiment was controlled.
You need to use the given strand of DNA and give an example of a substitution. So youd put for example maybe in the first part "CCA" youd substitute it with a " G" and thatd make it "GCA"