The answer is hox gene.
Hox genes are responsible for an embryo's body plan. They determine different body structures - legs, vertebrae, antennae, wings, depending on groups. Mutation in hox genes is serious mutation since it affects the early stages of embryo and consequently, normal development. If a mutation occurs in the hox gene for legs growth, the legs will not develop.
Answer:
Restoring force is a force which acts to bring a body to its equilibrium position. The restoring force is a function only of position of the mass or particle, and it is always directed back toward the equilibrium position. Therefore the restoring force of air particles should be displaced in the direction of the force and according to Newton 3rd law of motion, once the force is removed, restoring force of elasticity returns the displaced particle to a resting state .
<span>Lafora disease is the most severe teenage-onset progressive epilepsy, a unique form of glycogenosis with perikaryal accumulation of an abnormal form of glycogen, and a neurodegenerative disorder exhibiting an unusual generalized organellar disintegration. The disease is caused by mutations of the EPM2A gene, which encodes two isoforms of the laforin protein tyrosine phosphatase, having alternate carboxyl termini, one localized in the cytoplasm (endoplasmic reticulum) and the other in the nucleus. To date, all documented disease mutations, including the knockout mouse model deletion, have been in the segment of the protein common to both isoforms. It is therefore not known whether dysfunction of the cytoplasmic, nuclear, or both isoforms leads to the disease. In the present work, we identify six novel mutations, one of which, c.950insT (Q319fs), is the first mutation specific to the cytoplasmic laforin isoform, implicating this isoform in disease pathogenesis. To confirm this mutation's deleterious effect on laforin, we studied the resultant protein's subcellular localization and function and show a drastic reduction in its phosphatase activity, despite maintenance of its location at the endoplasmic reticulum.
I got my information from </span>https://www.ncbi.nlm.nih.gov/pubmed/14722920
Answer:
What is the name of this website
or the book?
