Well one would be constipation, when you are constipated you tend to get lower and upper back pain. Your liver and or kindness can cause back pain, a strained muscle or popped out disk can cause back pain. Alot of things can..
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A health care system in ancient Egypt was alot more loose, there were not many restrictions but it was not availible to everyone during that time
Answer:
What happens to the brain is the brain starts to adjust to the dopamine. And because of that the neurons will begin to make less dopamine. And less dopamine will signalise in the brain.