Prader-Willi syndrome (PWS) is a gentic disorder which has an impact on numerous physiological systems. PWS affected individuals (specifically babies) experience delayed growth, significant hypotonia (low muscle tone), and feeding issues. It does effect circadian rhythms in mice models.
SNORD116, often referred to as HBII-85, is a non-coding RNA (ncRNA) molecule that contributes to the alteration of other small nuclear RNAs (snRNAs). Unlike the majority of other snoRNAs, SNORD116 is not significantly complementary to ribosomal RNA and is expressed widely in the brain (but not in PWS patients).
According to the studies, SNORD116 cause sleep defect in patients with Prader-Willi syndrome. Same observation was seen in mouse models too. Paternal expression of SNORD116 is thought to be a potential gene for the sleep disruptions/circadian rhythm’s that the majority of PWS sufferers.
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Algea
Explanation:
Algea is a pioneer that will be find where glacier has retreated
Answer:two types of joints are fibrous or cartilaginous.
Explanation: An immovable joint connects the ends of the bones by a tough fibrous tissue.
Urbanization is the term that describes the Richardson family, who was tired of the congestion and crime associated with urban life, and then moved from their townhouse located in the middle of the city<span>to the suburbs</span>
Answer:
Due to their hole size.
Explanation:
Some molecules can pass directly through the phospholipid bilayer because of their small size which can easily pass through the small holes of phospholipid bilayer, while those that are too large or too charged need to pass through a membrane protein because membrane protein has a large holes through which large molecules can easily pass through the semi-permeable membrane of the cell by active or passive transport.
