Question

How would signaling be affected if a mutation caused a g protein to replace gdp with gtp on its own without needing to be activated by the g protein-coupled receptor?

Answer 1

Answer:

This mutation will produce a conformational change capable of maintaining the receptor continuously in its activated mode

Explanation:

G proteins are inactive when guanosine diphosphate (GDP) is bound, while they are active when guanosine triphosphate (GTP) is bound